Post‑cycle therapy (PCT) Use agents that restore natural hormone production (e.g., SERMs like tamoxifen).
Avoid mixing with other substances Stimulants or other anabolic agents can increase cardiovascular risk.
Legal status Be aware of local regulations; in many places anabolic steroids are illegal without prescription.
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7. Summary
Anabolic steroids (e.g., testosterone, nandrolone) and hormones (testosterone, DHEA) share the same basic mechanisms—binding to intracellular receptors that regulate gene transcription leading to protein synthesis.
The specific actions differ mainly in potency, half‑life, selectivity for muscle vs. bone, and side‑effect profiles. Steroids can produce rapid increases in lean body mass but also significant adverse effects (cardiovascular, hepatic, endocrine). Hormones like DHEA act more subtly and are often used as supplements rather than performance enhancers.
The difference lies in the chemical nature of the molecule, its pharmacokinetics, tissue distribution, and the extent to which it is converted into active forms or metabolites.
In short, steroids and hormones share a common biological pathway—binding to steroid receptors—but they differ substantially in how strongly they stimulate that pathway, how long they act, what tissues they affect, and what side effects they bring. This is why athletes must weigh the benefits of a stronger performance against the risks of serious health consequences.
